Monthly Archives: June 2012


Travel Grants Spring 2012 winner: Catarina Correia

And finally, a big round of applause for our first place travel grant winner, Dr. Catarina Correia! She researches protein interaction networks in autism spectrum disorders and presented her recent results at the International Meeting for Autism Research in Toronto, ON last month. We’re glad the travel grant helped her attend!  

I am currently pursuing a post-doctoral project at Instituto Gulbenkian de Ciência and Instituto Nacional de Saúde Dr. Ricardo Jorge (Portugal) working on the analysis of GWAS carried out by the Autism Genome Project (AGP), a large international consortium for autism genetics. My research aims to develop a network-based approach for GWAS data analysis by combining association results with protein-protein interaction data, and characterize potentially pathogenic CNVs identified in the AGP whole genome CNV analysis.  Read more…

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Travel Grants Spring 2012 winner: Malay Bhattacharyya

Congratulations to our second travel grant winner! Read on to find out how he uses NextBio Research to explore oncogenic microRNAs.In Malay’s words: 

I become truly amazed when I look back on my career and see how a student with undergraduate degrees in Computer Science and Electronics turned into a biology researcher. In the very first week of graduate school, I received an article on microRNAs (miRNAs), a class of short non-coding regulators of protein-coding genes, from my supervisor. Ever since that first read, I have been hooked on these endogeneous RNAs for four years and counting.  Read more…

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Chromatin clustering may hold cancer clues

Transcriptional regulators can change the way chromatin loops group together

Something like the image above is probably what comes to mind first when you hear ‘chromatin structure’. In reality, DNA spends only a small portion of time in these tightly coiled chromosomes. Most chromatin within cells lies in diffuse strands within nuclei. Mapping the locations of genes on these strands, scientists have found that chromatin containing more actively expressed genes tends to cluster together, as do chromatin strands containing inactive genes. Now, two recent papers show that these specific arrangements of chromatin may hold clues to developing targeted drugs for diseases like cancer. Read more…

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